Messi Biology Co., Ltd. of Hebei province states that the clinical application of pharmaceutical-grade magnesium hydroxide in antacids primarily involves alleviating various gastrointestinal discomforts caused by excessive stomach acid, such as heartburn, acid reflux, and stomach ulcers. Due to its rapid and effective acid-neutralizing action, magnesium hydroxide is widely used to treat acid-related conditions. A detailed description of its main clinical applications is as follows:
Excessive Stomach Acid (Hyperacidity): The most common clinical application of magnesium hydroxide is in the treatment of excessive stomach acid (acid reflux, heartburn, sour stomach, etc.). Hyperacidity is often caused by poor diet, stress, or certain digestive system disorders. Magnesium hydroxide helps alleviate these symptoms by neutralizing stomach acid. Clinically, magnesium hydroxide is usually administered in the form of oral suspensions or tablets, with the dosage generally determined by a doctor based on the severity of the patient’s symptoms.
Gastroesophageal Reflux Disease (GERD): GERD is a common digestive system disease in which patients often experience a burning sensation in the chest caused by refluxed stomach acid. By rapidly neutralizing stomach acid, magnesium hydroxide reduces the irritation of the lower esophagus by gastric acid, helping to alleviate symptoms triggered by gastroesophageal reflux. Compared to other antacids (such as H2 receptor antagonists and proton pump inhibitors), magnesium hydroxide has a faster onset of action and a shorter duration of effect, making it suitable for short-term symptom relief.
Gastric and Duodenal Ulcers: Magnesium hydroxide also plays a certain auxiliary role in the treatment of gastric and duodenal ulcers. By neutralizing stomach acid, magnesium hydroxide can reduce the corrosive effects of stomach acid on the stomach lining, thereby reducing pain and promoting ulcer healing. In some treatment regimens, magnesium hydroxide is used in combination with antibiotics (for the treatment of Helicobacter pylori infection) or other gastric medications to achieve better therapeutic outcomes.
Acute Gastritis: Acute gastritis is often caused by improper diet, drug side effects, or viral infections, leading to excessive stomach acid and stomach discomfort. By neutralizing stomach acid, magnesium hydroxide can effectively relieve symptoms such as stomach pain and heartburn.